Carlo Bifulco

h-index
h10-index
h5-index

Research activity per year

About

Dr. Bifulco is a Surgical Pathologist with additional fellowship subspecialty training, expertise, and board certification in Molecular Genetic Pathology and Hematopathology. Dr. Bifulco currently serves as Chief Medical Officer, Providence Genomics, and as Member and Director of Translational Molecular Pathology and Molecular Genomics at the Earle A. Chiles Research Institute in Portland, Oregon, a division of Providence Cancer Institute. He oversees Providence Molecular Genomics Laboratory, one of the largest clinical genomics labs in the Pacific Northwest, which provides state-of-the-art genomic sequencing to cancer patients across the seven state PSJH system.
 
Prior to joining Providence, Dr. Bifulco served on the Pathology faculty at Yale University and completed fellowships in Oncologic Surgical Pathology and Molecular Genetic Pathology at Memorial Sloan Kettering Cancer Center. His current translational research is focused on supporting the characterization of the tumor immune microenvironment through immunohistochemical and image analysis techniques, and on the integration of genomics with immunotherapies. Dr. Bifulco serves on the Global Colon Cancer Immunoscore Task Force led by the Society for Immunotherapy of Cancer (SITC), and is Co-Chair of the SITC Pathology Task Force convened to establish multiplexed immunohistochemistry/ immunofluorescence (mIHC/IF) standards.

Education/Academic qualification

Memorial Sloan Kettering Cancer Center

State University of Milan, Italy

Yale University

Yale-New Haven Hospital

External positions

Director, Providence Portland Medical Center

Jan 1 2011 → Jan 1 2019

Director, Providence Portland Medical Center

Jan 1 2011 → Jan 1 2019

NCCCP Biospecimens, Co-Lead, Providence Portland Medical Center

Jan 1 2010 → Jan 1 2012

NCCCP Biospecimens, Co-Lead, Providence Portland Medical Center

Jan 1 2010 → Jan 1 2012

Attending, Providence Portland Medical Center

Jan 1 2008 → …

Attending, Providence Portland Medical Center

Jan 1 2008 → …

Director, Yale University

Jan 1 2006 → Jan 1 2008

Assistant Professor, University of Florida

Jan 1 2003

Assistant Professor, University of Florida

Jan 1 2003

Assistant Professor, Yale University

Jan 1 2003 → Jan 1 2007

Assistant Professor, Yale University

Jan 1 2003 → Jan 1 2007

Director, National Cancer Institute, Milan, Italy

Jan 1 2001 → Jan 1 2002

Director, National Cancer Institute, Milan, Italy

Jan 1 2001 → Jan 1 2002

Attending, National Cancer Institute, Milan, Italy

Jan 1 2000 → Jan 1 2002

Attending, National Cancer Institute, Milan, Italy

Jan 1 2000 → Jan 1 2002

Fingerprint

Dive into the research topics where Carlo Bifulco is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

1 Similar Profiles

Applying machine learning techniques on routinely collected breast cancer data to improve patient outcomes
Bifulco, C. (PI)
01/1/20 → 01/1/21
Project: Research
Developmental Research Program Grant: Machine-learning-based identification and quantification of immune cell content from multiplex immunofluorescence histopathology images in the neoadjuvant immunoradiotherapy (NIRT) cohort
Bifulco, C. (CoI)
Providence Cancer Institute
01/1/20 → 01/1/21
Project: Research
Understand the composition of immune cells in a tumor biopsy
Bifulco, C. (CoI)
Oncosec
01/1/18 → 01/1/22
Project: Research
Multispectral IHC to delineate the tumor environment in AML and monitor fluctuations with flotetuzumab
Bifulco, C. (CoI)
MacroGenics
01/1/18 → 01/1/23
Project: Research
Intra-tumoral pre-surgical IO
Bifulco, C. (CoI)
BMS
01/1/16 → 01/1/19
Project: Research

169 Article
50 Other contribution
12 Review article
5 Comment/debate
More

Longitudinal multi-omic profiling of tissues and blood to track the molecular evolution of metastatic breast cancer
Kaplan, H. G., Dowdell, A. K., Wagner, J. T., Reynolds, S., Carney, C. A., Rosemon, J., Page, D. B., Conlin, A., McCormick, K., Yan, F., Johnston, E., File, D., Wahl, T., Lopez, J., Topp, Z., Paulson, K. G., Xie, B., Montgomery, S., Schnettler, E. & Sathyan, P. & 3 others, Bartlett, A. Q., Bifulco, C. & Piening, B. D., Feb 17 2026
Research output: Other contribution
Multimodal AI generates virtual population for tumor microenvironment modeling
Valanarasu, J. M. J., Xu, H., Usuyama, N., Kim, C., Wong, C., Argaw, P., Ben Shimol, R., Crabtree, A., Matlock, K., Bartlett, A. Q., Bagga, J., Gu, Y., Zhang, S., Naumann, T., Fox, B. A., Wright, B., Robicsek, A., Piening, B., Bifulco, C. & Wang, S. & 1 others, Poon, H., Jan 22 2026, In: Cell. 189, 2, p. 386-400.e19
Research output: Contribution to journal › Article › peer-review

Open Access
11 Scopus citations
Clinical validation of a multi-modal Ataraxis AI platform for recurrence prediction in early-stage breast cancer across multiple patient cohorts
Witowski, J., Choucair, K., Elayoubi, J., Chiru, E. D., Chan, N., Kang, Y. J., Howard, F. M., Ostrovnaya, I., Schnabel, F. R., Abdulsattar, W., Zong, Y., Daoud, L., Vetter, M., Pan, J. W., Laurinavičius, A., Piening, B., Bifulco, C. B., Brufsky, A., Esteva, F. J. & Pusztai, L., 2025, In: Journal of Clinical Oncology. 43, 16, 549.
Research output: Contribution to journal › Article › peer-review
Design and validation of a clinical whole genome sequencing-based assay for patient screening in a large healthcare system
Wagner, J. T., Welle, J. T., Lucas Beckett, I. A., Emery, K. R., Cosgrove, B. A., Olszewski, K., Wagner, N., Bower, T. C., Yuan, L. C., Shull, E. M., Jade, K., Clemens, J., Magis, A. T., Campbell, M. B., Gordon, O. K., Bifulco, C. B. & Piening, B. D., 2025, In: Frontiers in Molecular Biosciences. 12, 1669085.
Research output: Contribution to journal › Article › peer-review

Open Access
Geno4ME Study: implementation of whole genome sequencing for population screening in a large healthcare system
Lucas Beckett, I. A., Emery, K. R., Wagner, J. T., Jade, K., Cosgrove, B. A., Welle, J., Rinaldi, J. B., Dickey, L., Jones, K., Wagner, N., Shull, E. M., Clemens, J., Trachana, K., Anderson, L., Kudla, A., Smith, B., Verespej, H., Yuan, L. C., Denne, E. & Ramos, E. & 14 others, Lovejoy, J. C., Olszewski, K., Reese, M. G., Reynolds, M. J., Miller, M. M., Dowdell, A. K., Beck, B., Scanlan, J. M., Campbell, M. B., Magis, A. T., Vartanian, K., Piening, B. D., Bifulco, C. B. & Gordon, O. K., Dec 2025, In: npj Genomic Medicine. 10, 1, 50.
Research output: Contribution to journal › Article › peer-review

Open Access
3 Scopus citations

Carlo Bifulco, M.D.

Personal profile

About

Education/Academic qualification

External positions

Fingerprint

Collaborations and top research areas from the last five years

Dive into details

Applying machine learning techniques on routinely collected breast cancer data to improve patient outcomes

Developmental Research Program Grant: Machine-learning-based identification and quantification of immune cell content from multiplex immunofluorescence histopathology images in the neoadjuvant immunoradiotherapy (NIRT) cohort

Understand the composition of immune cells in a tumor biopsy

Multispectral IHC to delineate the tumor environment in AML and monitor fluctuations with flotetuzumab

Intra-tumoral pre-surgical IO

Longitudinal multi-omic profiling of tissues and blood to track the molecular evolution of metastatic breast cancer

Multimodal AI generates virtual population for tumor microenvironment modeling

Clinical validation of a multi-modal Ataraxis AI platform for recurrence prediction in early-stage breast cancer across multiple patient cohorts

Design and validation of a clinical whole genome sequencing-based assay for patient screening in a large healthcare system

Geno4ME Study: implementation of whole genome sequencing for population screening in a large healthcare system

Carlo Bifulco, M.D.

Personal profile

About

Education/Academic qualification

External positions

Fingerprint

Collaborations and top research areas from the last five years

Projects

Research output