Personal profile
Research interests
Computational biology, cancer, immuno-oncology, complex systems theory, machine learning
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Collaborations and top research areas from the last five years
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Spatiotemporal Tumor Analytics for Guiding Sequential Targeted-Inhibitor: Immunotherapy Combinations (ST-Analytics)
Heath, J. (PI), Ludwig, C. C. (CoPI), Shmulevich, I. (CoPI), Wei, W. (CoPI), Fan, R. R. (CoPI) & Thorsson, V. (CoPI)
09/22/22 → 08/31/26
Project: Research
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Prototype System for AML Digital Twins
Thorsson, V. (PI) & Shmulevich, I. (CoPI)
01/1/23 → 12/31/25
Project: Research
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DOCKET: accelerating knowledge extraction from biomedical data sets
Glusman, G. (PI), Shmulevich, I. (CoPI) & Hadlock, J. (CoPI)
National Center for Advancing Translational Sciences
01/24/20 → 11/30/23
Project: Research
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Integrative miRNA data analysis for clinical cancer genomics
Jones, S. J. (CoPI), Knijnenburg, T. (CoPI) & Shmulevich, I. (CoPI)
09/14/16 → 08/31/21
Project: Research
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Cellular heterogeneity and therapeutic response profiling of human IDH + glioma stem cell cultures
Chambwe, N., Kennedy, S. R., Kohrn, B. F., Lazarchuk, P., Leutert, M., Qin, G., Tercan, B., Sanchez-Contreras, M., Tang, W., Graber, J. J., Paddison, P. J., Villén, J., Shmulevich, I. & Monnat, R. J., Dec 2026, In: Scientific Reports. 16, 1, 3177.Research output: Contribution to journal › Article › peer-review
Open Access -
Predicting Microsatellite Instability from Whole Slide Images Using Texture Features
Swanson, N., Castro, M. A. A., Robertson, A. G., Shmulevich, I. & Tercan, B., 2026, Bioinformatics and Computational Biology - 21st Brazilian Conference, X-Meeting 2025, Proceedings. Dorn, M. & Martins Lopes, F. (eds.). Springer Science and Business Media Deutschland GmbH, p. 62-73 12 p. (Lecture Notes in Computer Science; vol. 16037 LNCS).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review
1 Scopus citations -
Classification of non-TCGA cancer samples to TCGA molecular subtypes using compact feature sets
The Cancer Genome Atlas Analysis Network, Feb 10 2025, In: Cancer Cell. 43, 2, p. 195-212.e11Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Digital twin models for predicting venetoclax and azacitidine-induced neutropenia in patients with acute myeloid leukemia
Zhang, Y., Martinez, J., Tercan, B., Kuusanmäki, H., Emmert-Streib, F., Chandraseelan, J. G., Farea, A., Yli-Harja, O., Heckman, C. A., Gibbs, D. L., Thorsson, V., Shmulevich, I., Kontro, M., Qin, G. & Aguilar, B., Dec 2025, In: npj Digital Medicine. 8, 1, 596.Research output: Contribution to journal › Article › peer-review
Open Access -
Medical digital twins: enabling precision medicine and medical artificial intelligence
Sadée, C., Testa, S., Barba, T., Hartmann, K., Schuessler, M., Thieme, A., Church, G. M., Okoye, I., Hernandez-Boussard, T., Hood, L., Shmulevich, I., Kuhl, E. & Gevaert, O., Jul 2025, In: The Lancet Digital Health. 7, 7, 100864.Research output: Contribution to journal › Review article › peer-review
Open Access39 Scopus citations