A Multi-omic Association Study of Trimethylamine N-Oxide

Ohad Manor; Niha Zubair; Matthew P. Conomos; Xiaojing Xu; Jesse E. Rohwer; Cynthia E. Krafft; Jennifer C. Lovejoy; Andrew T. Magis

doi:10.1016/j.celrep.2018.06.096

A Multi-omic Association Study of Trimethylamine N-Oxide

Ohad Manor
, Niha Zubair
, Matthew P. Conomos
, Xiaojing Xu
, Jesse E. Rohwer
, Cynthia E. Krafft
, Jennifer C. Lovejoy
, Andrew T. Magis

Research output: Contribution to journal › Article › peer-review

141 Scopus citations

Abstract

Trimethylamine N-oxide (TMAO) is a circulating metabolite that has been implicated in the development of atherosclerosis and cardiovascular disease. Manor et al. identify blood markers, metabolites, proteins, gut microbiota patterns, and diets that are significantly associated with levels of plasma TMAO.

Original language	English
Pages (from-to)	935-946
Number of pages	12
Journal	Cell Reports
Volume	24
Issue number	4
DOIs	https://doi.org/10.1016/j.celrep.2018.06.096
State	Published - Jul 24 2018

Keywords

CVD
TMAO
cardiovascular disease
metabolome
microbiome
multi-omic
trimethylamine N-oxide

Access to Document

10.1016/j.celrep.2018.06.096

Cite this

@article{23cf9498f55e4209b5a3a94812ba45d0,

title = "A Multi-omic Association Study of Trimethylamine N-Oxide",

abstract = "Trimethylamine N-oxide (TMAO) is a circulating metabolite that has been implicated in the development of atherosclerosis and cardiovascular disease. Manor et al. identify blood markers, metabolites, proteins, gut microbiota patterns, and diets that are significantly associated with levels of plasma TMAO.",

keywords = "CVD, TMAO, cardiovascular disease, metabolome, microbiome, multi-omic, trimethylamine N-oxide",

author = "Ohad Manor and Niha Zubair and Conomos, \{Matthew P.\} and Xiaojing Xu and Rohwer, \{Jesse E.\} and Krafft, \{Cynthia E.\} and Lovejoy, \{Jennifer C.\} and Magis, \{Andrew T.\}",

year = "2018",

month = jul,

day = "24",

doi = "10.1016/j.celrep.2018.06.096",

language = "English",

volume = "24",

pages = "935--946",

journal = "Cell Reports",

issn = "2639-1856",

publisher = "Elsevier B.V.",

number = "4",

}

TY - JOUR

T1 - A Multi-omic Association Study of Trimethylamine N-Oxide

AU - Manor, Ohad

AU - Zubair, Niha

AU - Conomos, Matthew P.

AU - Xu, Xiaojing

AU - Rohwer, Jesse E.

AU - Krafft, Cynthia E.

AU - Lovejoy, Jennifer C.

AU - Magis, Andrew T.

PY - 2018/7/24

Y1 - 2018/7/24

N2 - Trimethylamine N-oxide (TMAO) is a circulating metabolite that has been implicated in the development of atherosclerosis and cardiovascular disease. Manor et al. identify blood markers, metabolites, proteins, gut microbiota patterns, and diets that are significantly associated with levels of plasma TMAO.

AB - Trimethylamine N-oxide (TMAO) is a circulating metabolite that has been implicated in the development of atherosclerosis and cardiovascular disease. Manor et al. identify blood markers, metabolites, proteins, gut microbiota patterns, and diets that are significantly associated with levels of plasma TMAO.

KW - CVD

KW - TMAO

KW - cardiovascular disease

KW - metabolome

KW - microbiome

KW - multi-omic

KW - trimethylamine N-oxide

UR - https://www.scopus.com/pages/publications/85050162326

U2 - 10.1016/j.celrep.2018.06.096

DO - 10.1016/j.celrep.2018.06.096

M3 - Article

C2 - 30044989

AN - SCOPUS:85050162326

SN - 2639-1856

VL - 24

SP - 935

EP - 946

JO - Cell Reports

JF - Cell Reports

IS - 4

ER -

A Multi-omic Association Study of Trimethylamine N-Oxide

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this