TY - JOUR
T1 - Cancer case trends following the onset of the COVID-19 pandemic
T2 - A community-based observational study with extended follow-up
AU - Drescher, Charles W.
AU - Bograd, Adam J.
AU - Chang, Shu Ching
AU - Weerasinghe, Roshanthi K.
AU - Vita, Ann
AU - Bell, R. Bryan
N1 - Publisher Copyright:
© 2021 American Cancer Society
PY - 2022/4/1
Y1 - 2022/4/1
N2 - Background: The coronavirus disease 2019 (COVID-19) pandemic has impacted health care delivery worldwide. Cancer is a leading cause of death, and the impact of the pandemic on cancer diagnoses is an important public health concern. Methods: This cross-sectional study retrospectively analyzed the electronic medical records of 80,138 cancer patients diagnosed between January 1, 2019, and May 31, 2021. Outcome measures included weekly number of new cancer cases and trends in weekly cancer cases, before and after the pandemic; patient demographics; and positive COVID-19 test rates. Results: Beginning March 4, 2020, defined as the onset of the pandemic, weekly cancer cases declined precipitously (–110.0 cases per week [95% confidence interval, −190.2 to −29.8]) for 4 weeks, followed by a moderate recovery (+23.7 cases per week [9.1 to 38.4]) of 10 weeks duration. Thereafter, weekly cancer cases trended slowly back toward pre-COVID-19 baseline levels. Following the pandemic onset, there was a cumulative year-over-year decline in cancer cases overall of 7.3%, including a 20.2%, 14.3%, and 12.8% decline in nonmelanoma skin cancer, breast cancer, and prostate cancer, respectively. Changes in case volumes were accompanied by variations in patient characteristics, including region, age, gender, race, insurance coverage, and COVID-19 positive test rates (P <.01 for all). Among patients tested for COVID-19, 5.3% had a positive result. Conclusions: The data in this study demonstrate a substantial reduction in cancer diagnoses following the onset of COVID-19, which appear to reach expected pre-COVID norms 12 months later. The largest reduction was noted among cancers that are typically screen-detected or identified as part of a routine wellness examination.
AB - Background: The coronavirus disease 2019 (COVID-19) pandemic has impacted health care delivery worldwide. Cancer is a leading cause of death, and the impact of the pandemic on cancer diagnoses is an important public health concern. Methods: This cross-sectional study retrospectively analyzed the electronic medical records of 80,138 cancer patients diagnosed between January 1, 2019, and May 31, 2021. Outcome measures included weekly number of new cancer cases and trends in weekly cancer cases, before and after the pandemic; patient demographics; and positive COVID-19 test rates. Results: Beginning March 4, 2020, defined as the onset of the pandemic, weekly cancer cases declined precipitously (–110.0 cases per week [95% confidence interval, −190.2 to −29.8]) for 4 weeks, followed by a moderate recovery (+23.7 cases per week [9.1 to 38.4]) of 10 weeks duration. Thereafter, weekly cancer cases trended slowly back toward pre-COVID-19 baseline levels. Following the pandemic onset, there was a cumulative year-over-year decline in cancer cases overall of 7.3%, including a 20.2%, 14.3%, and 12.8% decline in nonmelanoma skin cancer, breast cancer, and prostate cancer, respectively. Changes in case volumes were accompanied by variations in patient characteristics, including region, age, gender, race, insurance coverage, and COVID-19 positive test rates (P <.01 for all). Among patients tested for COVID-19, 5.3% had a positive result. Conclusions: The data in this study demonstrate a substantial reduction in cancer diagnoses following the onset of COVID-19, which appear to reach expected pre-COVID norms 12 months later. The largest reduction was noted among cancers that are typically screen-detected or identified as part of a routine wellness examination.
KW - cancer
KW - coronavirus
KW - coronavirus disease 2019 (COVID-19)
KW - pandemic
KW - severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
UR - http://www.scopus.com/inward/record.url?scp=85121460132&partnerID=8YFLogxK
U2 - 10.1002/cncr.34067
DO - 10.1002/cncr.34067
M3 - Article
C2 - 34919267
AN - SCOPUS:85121460132
SN - 0008-543X
VL - 128
SP - 1475
EP - 1482
JO - Cancer
JF - Cancer
IS - 7
ER -