Abstract
Marijuana is a complex substance containing over 60 different forms of cannabinoids, the active ingredients. Cannabinoids are now known to have the capacity for neuromodulation, via direct, receptor-based mechanisms at numerous levels within the nervous system. These have therapeutic properties that may be applicable to the treatment of neurological disorders; including anti-oxidative, neuroprotective, analgesic and anti-inflammatory actions; immunomodulation, modulation of glial cells and tumor growth regulation. This article reviews the emerging research on the physiological mechanisms of endogenous and exogenous cannabinoids in the context of neurological disease.
| Original language | English |
|---|---|
| Pages (from-to) | 437-440 |
| Number of pages | 4 |
| Journal | Current Opinion in Investigational Drugs |
| Volume | 3 |
| Issue number | 3 |
| State | Published - 2002 |