Down syndrome associated moyamoya may worsen epilepsy control and can benefit from surgical revascularization.

Sarah R Garson; Stephen J Monteith; Sheila D Smith; Bart P Keogh; Ryder P Gwinn; Michael J Doherty

Down syndrome associated moyamoya may worsen epilepsy control and can benefit from surgical revascularization.

Sarah R Garson
, Stephen J Monteith
, Sheila D Smith
, Bart P Keogh
, Ryder P Gwinn
, Michael J Doherty

Research output: Contribution to journal › Article › peer-review

Abstract

Objectives: To examine outcome of bilateral extracranial to intracranial (EC-IC) bypass surgeries for a Down syndrome patient with hard-to-treat epilepsy and moyamoya.

Materials and methods: Superficial temporal arteries were anastamosed using an indirect bypass technique to middle cerebral arteries bilaterally to help limit perfusion deficits and seizure controls.

Results: Two superficial temporal to middle cerebral artery indirect bypass surgeries were performed within 3 months. Post-revascularization improvements included seizure control, gait, perfusion, wakefulness, language and quality of life.

Conclusion: In patients with Down syndrome and moyamoya, improvements in seizure control and quality of life may occur with EC-IC bypass procedures.

Original language	American English
Journal	Epilepsy Behav Case Rep
State	Published - Jan 1 2019

Keywords

Bypass
Perfusion
Stenosis

Disciplines

Neurology
Surgery

Access to Document

Cite this

@article{34479eabc4814d3886d945f783131e94,

title = "Down syndrome associated moyamoya may worsen epilepsy control and can benefit from surgical revascularization.",

abstract = " Objectives: To examine outcome of bilateral extracranial to intracranial (EC-IC) bypass surgeries for a Down syndrome patient with hard-to-treat epilepsy and moyamoya. Materials and methods: Superficial temporal arteries were anastamosed using an indirect bypass technique to middle cerebral arteries bilaterally to help limit perfusion deficits and seizure controls. Results: Two superficial temporal to middle cerebral artery indirect bypass surgeries were performed within 3 months. Post-revascularization improvements included seizure control, gait, perfusion, wakefulness, language and quality of life. Conclusion: In patients with Down syndrome and moyamoya, improvements in seizure control and quality of life may occur with EC-IC bypass procedures.",

keywords = "Bypass, Perfusion, Stenosis",

author = "Garson, \{Sarah R\} and Monteith, \{Stephen J\} and Smith, \{Sheila D\} and Keogh, \{Bart P\} and Gwinn, \{Ryder P\} and Doherty, \{Michael J\}",

year = "2019",

month = jan,

day = "1",

language = "American English",

journal = "Epilepsy Behav Case Rep",

}

TY - JOUR

T1 - Down syndrome associated moyamoya may worsen epilepsy control and can benefit from surgical revascularization.

AU - Garson, Sarah R

AU - Monteith, Stephen J

AU - Smith, Sheila D

AU - Keogh, Bart P

AU - Gwinn, Ryder P

AU - Doherty, Michael J

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Objectives: To examine outcome of bilateral extracranial to intracranial (EC-IC) bypass surgeries for a Down syndrome patient with hard-to-treat epilepsy and moyamoya. Materials and methods: Superficial temporal arteries were anastamosed using an indirect bypass technique to middle cerebral arteries bilaterally to help limit perfusion deficits and seizure controls. Results: Two superficial temporal to middle cerebral artery indirect bypass surgeries were performed within 3 months. Post-revascularization improvements included seizure control, gait, perfusion, wakefulness, language and quality of life. Conclusion: In patients with Down syndrome and moyamoya, improvements in seizure control and quality of life may occur with EC-IC bypass procedures.

AB - Objectives: To examine outcome of bilateral extracranial to intracranial (EC-IC) bypass surgeries for a Down syndrome patient with hard-to-treat epilepsy and moyamoya. Materials and methods: Superficial temporal arteries were anastamosed using an indirect bypass technique to middle cerebral arteries bilaterally to help limit perfusion deficits and seizure controls. Results: Two superficial temporal to middle cerebral artery indirect bypass surgeries were performed within 3 months. Post-revascularization improvements included seizure control, gait, perfusion, wakefulness, language and quality of life. Conclusion: In patients with Down syndrome and moyamoya, improvements in seizure control and quality of life may occur with EC-IC bypass procedures.

KW - Bypass

KW - Perfusion

KW - Stenosis

UR - https://digitalcommons.psjhealth.org/publications/902

M3 - Article

JO - Epilepsy Behav Case Rep

JF - Epilepsy Behav Case Rep

ER -

Down syndrome associated moyamoya may worsen epilepsy control and can benefit from surgical revascularization.

Abstract

Keywords

Disciplines

Access to Document

Other files and links

Fingerprint

Cite this