Immune gene signatures and integrative spatially-resolved digital profiling of prognostic biomarkers for mesothelioma.

Sarah Elizabeth Church; Carmen Ballesteros-Merino; Amy H Sullivan; Andrew M White; Michael D Bailey; Shawn M Jensen; John R Handy; Rachel E. Sanborn; Carlo Bruno Bifulco; Sarah Warren; Joseph M Beechem; Bernard A. Fox

doi:10.1200/JCO.2019.37.15_SUPPL.E20071

Immune gene signatures and integrative spatially-resolved digital profiling of prognostic biomarkers for mesothelioma.

Sarah Elizabeth Church
, Carmen Ballesteros-Merino
, Amy H Sullivan
, Andrew M White
, Michael D Bailey
, Shawn M Jensen
, John R Handy
, Rachel E. Sanborn
, Carlo Bruno Bifulco
, Sarah Warren
, Joseph M Beechem
, Bernard A. Fox

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Journal of Clinical Oncology
Volume	37
DOIs	https://doi.org/10.1200/JCO.2019.37.15_SUPPL.E20071
State	Published - May 26 2019

Disciplines

Medicine and Health Sciences
Oncology

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Church, S. E., Ballesteros-Merino, C., Sullivan, A. H., White, A. M., Bailey, M. D., Jensen, S. M., Handy, J. R., Sanborn, R. E., Bifulco, C. B., Warren, S., Beechem, J. M., & Fox, B. A. (2019). Immune gene signatures and integrative spatially-resolved digital profiling of prognostic biomarkers for mesothelioma. Journal of Clinical Oncology, 37. https://doi.org/10.1200/JCO.2019.37.15_SUPPL.E20071

@article{b6d0a381c3c948ec9682d4e9f8d46e82,

title = "Immune gene signatures and integrative spatially-resolved digital profiling of prognostic biomarkers for mesothelioma.",

author = "Church, \{Sarah Elizabeth\} and Carmen Ballesteros-Merino and Sullivan, \{Amy H\} and White, \{Andrew M\} and Bailey, \{Michael D\} and Jensen, \{Shawn M\} and Handy, \{John R\} and Sanborn, \{Rachel E.\} and Bifulco, \{Carlo Bruno\} and Sarah Warren and Beechem, \{Joseph M\} and Fox, \{Bernard A.\}",

note = "e20071 Background: Malignant mesothelioma has been an incurable disease with few effective therapies. While PD-1 targeted therapies have elicited some patient responses, the overall response rate for mesothelioma is low. Since mesothelioma is derived from the mesothelium of the lung, we hypothesize that immune cells in the tumor microenvironment (TME) may behave differently than other solid tumors that are responsive to immunotherapy.",

year = "2019",

month = may,

day = "26",

doi = "10.1200/JCO.2019.37.15\_SUPPL.E20071",

language = "American English",

volume = "37",

journal = "Journal of Clinical Oncology",

}

Church, SE, Ballesteros-Merino, C, Sullivan, AH, White, AM, Bailey, MD, Jensen, SM, Handy, JR, Sanborn, RE, Bifulco, CB, Warren, S, Beechem, JM & Fox, BA 2019, 'Immune gene signatures and integrative spatially-resolved digital profiling of prognostic biomarkers for mesothelioma.', Journal of Clinical Oncology, vol. 37. https://doi.org/10.1200/JCO.2019.37.15_SUPPL.E20071

TY - JOUR

T1 - Immune gene signatures and integrative spatially-resolved digital profiling of prognostic biomarkers for mesothelioma.

AU - Church, Sarah Elizabeth

AU - Ballesteros-Merino, Carmen

AU - Sullivan, Amy H

AU - White, Andrew M

AU - Bailey, Michael D

AU - Jensen, Shawn M

AU - Handy, John R

AU - Sanborn, Rachel E.

AU - Bifulco, Carlo Bruno

AU - Warren, Sarah

AU - Beechem, Joseph M

AU - Fox, Bernard A.

N1 - e20071 Background: Malignant mesothelioma has been an incurable disease with few effective therapies. While PD-1 targeted therapies have elicited some patient responses, the overall response rate for mesothelioma is low. Since mesothelioma is derived from the mesothelium of the lung, we hypothesize that immune cells in the tumor microenvironment (TME) may behave differently than other solid tumors that are responsive to immunotherapy.

PY - 2019/5/26

Y1 - 2019/5/26

UR - https://ascopubs.org/doi/abs/10.1200/JCO.2019.37.15_suppl.e20071

U2 - 10.1200/JCO.2019.37.15_SUPPL.E20071

DO - 10.1200/JCO.2019.37.15_SUPPL.E20071

M3 - Article

VL - 37

JO - Journal of Clinical Oncology

JF - Journal of Clinical Oncology

ER -

Immune gene signatures and integrative spatially-resolved digital profiling of prognostic biomarkers for mesothelioma.

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