Lidocaine for Severe Hiccups

Mordecai N. Dunst, Kim Margolin, David Horak

Research output: Contribution to journalLetterpeer-review

20 Scopus citations

Abstract

To the Editor: The pharmacologic approaches to the treatment of severe hiccups include the use of chlorpromazine, carbamazepine, nifedipine, baclofen, metoclopramide, haloperidol, ketamine, and phenytoin, each of which has potentially serious side effects1,2. Pretreatment with intravenous lidocaine (1 mg per kilogram of body weight) diminishes hiccups that are associated with the induction of anesthesia with methohexital3. We report the use of intravenous lidocaine to treat incapacitating hiccups. A 45-year-old man was hospitalized with fever and pulmonary infiltrate. Two days after bronchoscopy, intense, nearly continuous hiccups developed, associated with nausea, chest pain, dizziness, and fatigue. Oral medications were…

Original languageEnglish
Pages (from-to)890-891
Number of pages2
JournalNew England Journal of Medicine
Volume329
Issue number12
DOIs
StatePublished - Sep 16 1993

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