Modification of Experimental Aminoglycoside Nephrotoxicity

William M. Bennett; Craig A. Wood; Donald C. Houghton; David N. Gilbert

doi:10.1016/S0272-6386(86)80100-7

Modification of Experimental Aminoglycoside Nephrotoxicity

William M. Bennett
, Craig A. Wood
, Donald C. Houghton
, David N. Gilbert

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Some of the factors that modify experimental aminoglycoside nephrotoxicity are reviewed. Maneuvers ready to be tested for effectiveness in the clinical use of these drugs are highlighted. The use of concomitant penicillins and changes in dosing strategy seem to be particularly exciting new leads toward elimination of clinical aminoglycoside nephrotoxicity.

Original language	English
Pages (from-to)	292-296
Number of pages	5
Journal	American Journal of Kidney Diseases
Volume	8
Issue number	5
DOIs	https://doi.org/10.1016/S0272-6386(86)80100-7
State	Published - 1986

Keywords

Aminoglycosides
gentamicin
nephrotoxicity
ticarcillin
tobramycin

Access to Document

10.1016/S0272-6386(86)80100-7

Cite this

@article{36d6d9f92267491c94c61b02efd47944,

title = "Modification of Experimental Aminoglycoside Nephrotoxicity",

abstract = "Some of the factors that modify experimental aminoglycoside nephrotoxicity are reviewed. Maneuvers ready to be tested for effectiveness in the clinical use of these drugs are highlighted. The use of concomitant penicillins and changes in dosing strategy seem to be particularly exciting new leads toward elimination of clinical aminoglycoside nephrotoxicity.",

keywords = "Aminoglycosides, gentamicin, nephrotoxicity, ticarcillin, tobramycin",

author = "Bennett, \{William M.\} and Wood, \{Craig A.\} and Houghton, \{Donald C.\} and Gilbert, \{David N.\}",

note = "Funding Information: From the Department of Medicine and Pathology, Oregon Health Sciences University, and Chiles Research Foundation Providence Medical Center, Portland, OR. Authors studies cited in this paper were supported by grants from Nephrology Research Associates and the Eli Lilly Company. Address reprint requests to William M. Bennett, MD, Division of Nephrology, Department of Medicine, L-463, Oregon Health Sciences University, Portland, OR 97201. {\textcopyright} 1986 by the National Kidney Foundation, Inc. 0272-6386/86/0805-0002\$03.00/0",

year = "1986",

doi = "10.1016/S0272-6386(86)80100-7",

language = "English",

volume = "8",

pages = "292--296",

journal = "American Journal of Kidney Diseases",

issn = "0272-6386",

publisher = "W.B. Saunders",

number = "5",

}

TY - JOUR

T1 - Modification of Experimental Aminoglycoside Nephrotoxicity

AU - Bennett, William M.

AU - Wood, Craig A.

AU - Houghton, Donald C.

AU - Gilbert, David N.

N1 - Funding Information: From the Department of Medicine and Pathology, Oregon Health Sciences University, and Chiles Research Foundation Providence Medical Center, Portland, OR. Authors studies cited in this paper were supported by grants from Nephrology Research Associates and the Eli Lilly Company. Address reprint requests to William M. Bennett, MD, Division of Nephrology, Department of Medicine, L-463, Oregon Health Sciences University, Portland, OR 97201. © 1986 by the National Kidney Foundation, Inc. 0272-6386/86/0805-0002$03.00/0

PY - 1986

Y1 - 1986

N2 - Some of the factors that modify experimental aminoglycoside nephrotoxicity are reviewed. Maneuvers ready to be tested for effectiveness in the clinical use of these drugs are highlighted. The use of concomitant penicillins and changes in dosing strategy seem to be particularly exciting new leads toward elimination of clinical aminoglycoside nephrotoxicity.

AB - Some of the factors that modify experimental aminoglycoside nephrotoxicity are reviewed. Maneuvers ready to be tested for effectiveness in the clinical use of these drugs are highlighted. The use of concomitant penicillins and changes in dosing strategy seem to be particularly exciting new leads toward elimination of clinical aminoglycoside nephrotoxicity.

KW - Aminoglycosides

KW - gentamicin

KW - nephrotoxicity

KW - ticarcillin

KW - tobramycin

UR - https://www.scopus.com/pages/publications/0022919933

U2 - 10.1016/S0272-6386(86)80100-7

DO - 10.1016/S0272-6386(86)80100-7

M3 - Article

C2 - 3788967

AN - SCOPUS:0022919933

SN - 0272-6386

VL - 8

SP - 292

EP - 296

JO - American Journal of Kidney Diseases

JF - American Journal of Kidney Diseases

IS - 5

ER -

Modification of Experimental Aminoglycoside Nephrotoxicity

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this