Abstract
PURPOSE: Targeted Agent and Profiling Utilization Registry is a phase II basket trial evaluating the antitumor activity of commercially available targeted agents in patients with advanced cancer and genomic alterations known to be drug targets. Results of a cohort of patients with biliary tract cancer (BTC) with
METHODS: Eligible patients had advanced BTC, measurable disease (RECIST v1.1), Eastern Cooperative Oncology Group performance status 0-2, adequate organ function, tumors with
RESULTS: Twenty-nine patients were enrolled from February 2017 to January 2022, and all had advanced BTC with an
CONCLUSION: Pertuzumab plus trastuzumab met prespecified criteria to declare a signal of activity in patients with BTC and
Original language | Undefined/Unknown |
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Journal | Articles, Abstracts, and Reports |
State | Published - May 15 2024 |