TY - JOUR
T1 - Prevention of lung cancer
AU - Goodman, Gary E.
PY - 1998
Y1 - 1998
N2 - Lung cancer chemoprevention continued to make progress in 1997. The incidence of tobacco abuse continues to slowly fall in the United States, and paralleling it, lung cancer incidence. Biomarkers of carcinogenesis and susceptibility continue to be an important area in identifying high-risk patients. The analyses of two major lung cancer prevention trials, β-Carotene and Retinol Efficacy Trial (CARET) and Alpha-Tocopherol Beta-Carotene (ATBC), were also published this past year. Both found an increased incidence of lung cancer in individuals receiving beta-carotene, in both trials, heavy smokers seem to be the most adversely affected group. The mechanism of this increased incidence of cancer and total deaths still eludes investigators.
AB - Lung cancer chemoprevention continued to make progress in 1997. The incidence of tobacco abuse continues to slowly fall in the United States, and paralleling it, lung cancer incidence. Biomarkers of carcinogenesis and susceptibility continue to be an important area in identifying high-risk patients. The analyses of two major lung cancer prevention trials, β-Carotene and Retinol Efficacy Trial (CARET) and Alpha-Tocopherol Beta-Carotene (ATBC), were also published this past year. Both found an increased incidence of lung cancer in individuals receiving beta-carotene, in both trials, heavy smokers seem to be the most adversely affected group. The mechanism of this increased incidence of cancer and total deaths still eludes investigators.
UR - http://www.scopus.com/inward/record.url?scp=0031932956&partnerID=8YFLogxK
U2 - 10.1097/00001622-199803000-00007
DO - 10.1097/00001622-199803000-00007
M3 - Short survey
C2 - 9555534
AN - SCOPUS:0031932956
SN - 1040-8746
VL - 10
SP - 122
EP - 126
JO - Current Opinion in Oncology
JF - Current Opinion in Oncology
IS - 2
ER -