Seizure control: A secondary benefit of chemotherapeutic temozolomide in brain cancer patients

Alexander Hu; Zhiqiang Xu; Ryan Y. Kim; Angel Nguyen; Jong Woo Lee; Santosh Kesari

doi:10.1016/j.eplepsyres.2011.03.018

Seizure control: A secondary benefit of chemotherapeutic temozolomide in brain cancer patients

Alexander Hu
, Zhiqiang Xu
, Ryan Y. Kim
, Angel Nguyen
, Jong Woo Lee
, Santosh Kesari

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

The severity of brain tumor associated seizures often mirror the growth of the underlying tumor, and may be intractable to conventional antiepileptic drugs. We present a patient with intractable seizures in the setting of a low grade glioma who responded dramatically to temozolomide despite minimal radiographic change in tumor size. Temozolomide is an effective treatment for seizure control in patients with brain tumors.

Original language	English
Pages (from-to)	270-272
Number of pages	3
Journal	Epilepsy Research
Volume	95
Issue number	3
DOIs	https://doi.org/10.1016/j.eplepsyres.2011.03.018
State	Published - Aug 2011

Keywords

Antiepileptic drugs
Brain tumor
Chemotherapy
Seizure
Temozolomide

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10.1016/j.eplepsyres.2011.03.018

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title = "Seizure control: A secondary benefit of chemotherapeutic temozolomide in brain cancer patients",

abstract = "The severity of brain tumor associated seizures often mirror the growth of the underlying tumor, and may be intractable to conventional antiepileptic drugs. We present a patient with intractable seizures in the setting of a low grade glioma who responded dramatically to temozolomide despite minimal radiographic change in tumor size. Temozolomide is an effective treatment for seizure control in patients with brain tumors.",

keywords = "Antiepileptic drugs, Brain tumor, Chemotherapy, Seizure, Temozolomide",

author = "Alexander Hu and Zhiqiang Xu and Kim, \{Ryan Y.\} and Angel Nguyen and Lee, \{Jong Woo\} and Santosh Kesari",

year = "2011",

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language = "English",

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journal = "Epilepsy Research",

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T2 - A secondary benefit of chemotherapeutic temozolomide in brain cancer patients

AU - Hu, Alexander

AU - Xu, Zhiqiang

AU - Kim, Ryan Y.

AU - Nguyen, Angel

AU - Lee, Jong Woo

AU - Kesari, Santosh

PY - 2011/8

Y1 - 2011/8

N2 - The severity of brain tumor associated seizures often mirror the growth of the underlying tumor, and may be intractable to conventional antiepileptic drugs. We present a patient with intractable seizures in the setting of a low grade glioma who responded dramatically to temozolomide despite minimal radiographic change in tumor size. Temozolomide is an effective treatment for seizure control in patients with brain tumors.

AB - The severity of brain tumor associated seizures often mirror the growth of the underlying tumor, and may be intractable to conventional antiepileptic drugs. We present a patient with intractable seizures in the setting of a low grade glioma who responded dramatically to temozolomide despite minimal radiographic change in tumor size. Temozolomide is an effective treatment for seizure control in patients with brain tumors.

KW - Antiepileptic drugs

KW - Brain tumor

KW - Chemotherapy

KW - Seizure

KW - Temozolomide

UR - https://www.scopus.com/pages/publications/79960359625

U2 - 10.1016/j.eplepsyres.2011.03.018

DO - 10.1016/j.eplepsyres.2011.03.018

M3 - Article

C2 - 21549564

AN - SCOPUS:79960359625

SN - 0920-1211

VL - 95

SP - 270

EP - 272

JO - Epilepsy Research

JF - Epilepsy Research

IS - 3

ER -

Seizure control: A secondary benefit of chemotherapeutic temozolomide in brain cancer patients

Abstract

Keywords

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