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Testosterone-producing benign cystic teratoma with virilism: A case report

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8 Scopus citations

Abstract

BACKGROUND: Mature cystic teratomas are common tumors in reproductive- age women. Biologic activity in a small percentage of these neoplasms is well recognized. Thyroid hormone is the most commonly secreted substance. CASE: A 25-year-old woman presented with a large abdominal mass and virilism. Preoperative evaluation revealed elevated creatinine and testosterone levels and anemia. Computed tomography (CT) showed fat-fluid levels and multiple calcifications within the mass and obstruction of the right kidney. At surgery a 30-cm left ovarian mass was removed. Left ovarian vein testosterone levels were markedly elevated. Pathology reported a mature cystic teratoma. Postoperatively the testosterone levels returned to normal. CONCLUSION: In rare instances androgen production and virilization may occur with mature cystic teratoma.

Original languageEnglish
Pages (from-to)924-926
Number of pages3
JournalJournal of Reproductive Medicine for the Obstetrician and Gynecologist
Volume41
Issue number12
StatePublished - Dec 1996
Externally publishedYes

Keywords

  • teratoma, cystic
  • teratoma, mature
  • testosterone
  • virilism

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