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The Prevalence of Y-chromosome Microdeletions in Oligozoospermic Men: A Systematic Review and Meta-analysis of European and North American Studies(Figure presented.)

  • Taylor P. Kohn
  • , Jaden R. Kohn
  • , Ryan C. Owen
  • , R. Matthew Coward

Research output: Contribution to journalReview articlepeer-review

55 Scopus citations

Abstract

Complete Y-chromosome microdeletions (YCMs) are rarely found in men with sperm concentrations of 1–5 million sperm/ml. North American and European guidelines should be reconsidered, and clinicians do not need routine YCM screening if sperm concentrations are >1 million sperm/ml.

Original languageEnglish
Pages (from-to)626-636
Number of pages11
JournalEuropean Urology
Volume76
Issue number5
DOIs
StatePublished - Nov 2019
Externally publishedYes

Keywords

  • Gene deletion
  • Genetics
  • Infertility
  • Meta-analysis
  • Semen analysis
  • Y chromosome

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