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Top Ten Tips Palliative Care Clinicians Should Know About Caring for People with Leptomeningeal Disease

  • Alice Hawkins
  • , Mariana Khawand-Azoulai
  • , Rachel Tanenbaum
  • , Carina Oltmann
  • , Carolina Benjamin
  • , Tejan Diwanji
  • , Maria del Pilar Guillermo Prieto Eibl
  • , Cara L. Siegel
  • , Akanksha Sharma

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Leptomeningeal disease (LMD), spread of cancer to the lining of the brain and its protective coverings, is a feared complication of many different types of cancer. LMD negatively affects prognosis across tumor types. Palliative care (PC) clinicians caring for patients with advanced cancer may be faced with discussing limited prognosis, assisting with symptom management, and helping with medical decision making for patients with LMD. An understanding of pathophysiology, symptomatology, prognosis, and treatment options is essential in providing optimal care. This article, written by clinicians who work across the cancer spectrum, uses an accessible “ten tips” format to help increase PC providers’ confidence and competence around caring for people with LMD.

Original languageEnglish
Pages (from-to)960-966
Number of pages7
JournalJournal of Palliative Medicine
Volume28
Issue number7
DOIs
StatePublished - Jul 1 2025
Externally publishedYes

Keywords

  • cerebellar symptoms
  • hematologic malignancy
  • leptomeningeal disease
  • neurological symptoms
  • palliative care
  • prognosis

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