Human Tumor Atlas Network: Data Coordinating Center Extension

Project Summary/Abstract We propose to continue managing the operations of the data coordinating center (DCC) for the Human Tumor Atlas Network (HTAN) with responsibilities for managing, curating, and disseminating the data and resources generated through this network. We have provided, and will continue to provide, key services to organize and support the Research Centers that comprise the network, and foster a community based on collaboration, transparency, and sharing. Our primary scientific objective is to accelerate the discovery of mechanisms governing tumorigenesis, progression, and evolution, which will lead to improved prevention and treatment strategies for patients. We aim to achieve this by providing technology services coupled with best practices to expedite data acquisition and dissemination to HTAN researchers, as well as the broader scientific community. HTAN data is now available via the HTAN Data Portal, the Synapse platform, Minerva, CellXGene, cBioPortal, Google BigQuery, the NCI Cancer Research Data Service (CDS) and the NCI Image Data Commons (IDC). We will continue to release HTAN data to the wider scientific community and further develop visualization, annotation, and analysis tools in order to meet the needs of HTAN and the diverse cancer research community – including data scientists and statisticians to biologists and clinicians – as new types of data are generated.